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Apoptosis in arsenic trioxide-treated Calu-6 lung cells is correlated with the depletion of GSH levels rather than the changes of ROS levels

Drug Alcohol Depend 160:135142

Such a nanosystem could activate cisplatin by exhausting the intracellular GSH, which elevated the Pt-induced DNA intrastrand or interstrand crosslinks, thereby contributing to the anticancer efficiency of platinum drugs

In contrast, the placebo group resulted in increased levels of IL-6 or the same levels of IL-6 in plasma ( Figure 4A )

Most sessions take about 45 to 60 minutes

A randomized, double-blind, placebo-controlled study used topical oxidized glutathione (GSSG) 2% lotion applied twice daily for 10 weeks in 30 women