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Look for dehydration or other complications
Phase 1: Retatrutide foundation (weeks 1-8) During this initial phase, the goal is to establish retatrutide tolerance before adding cagrilintide
Like with tirzepatide, this separation suggests combination potential, though no clinical trials have evaluated this pairing
Exclusivity Upon NDA approval of a new chemical entity, or NCE, which is a drug that contains no active moiety that has been approved by FDA in any other NDA, that drug receives five years of exclusivity during which FDA may not receive any ANDA seeking approval of a generic version of that drug
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