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This complexity highlights the critical need for a deeper understanding of its underlying pathophysiological mechanisms and the development of more targeted therapeutic approaches

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ThDP is used as a cofactor for the microbial enzyme pyruvate-ferredoxin oxidoreductase, which catalyzes the conversion of pyruvate to acetyl-CoA in the pathway for butyrate synthesis (56)

M., Setti, T., Mosaner, T., Simplicio, C

32 McCoyA

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