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5 There is increased aromatase, which produces estrogen, as well as decreased 17-hydroxysteroid dehydrogenase 2 (17-HSD2), which breaks down estradiol to estrone, a more inert form of estrogen

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Diabetologia1979 Feb;16(2):75-85

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A systematic review ScienceDirect science/article/pii/S2214623724000048 [58] GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)

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In a 2024 joint court filing, the two companies said that the safety profile of GLP-1 RAs has been well-established in hundreds of clinical trials, large-scale observational studies, and nearly two decades of real-world use

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Epub 2011 Nov 1

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