An in vitro study was conducted using pancreatic -cell line, MIN-6, stably expressing GLP-1R (GLP-1R-MIN-6 cells) and intestinal L-cell line, GLUTag
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Peptides (1995) 16(4):75771
Selleck, TX, USA), diluted with sterile saline, was injected i.p
It is clear that the CNS is necessary for GLP-1R mediated induction of visceral illness as mice with a CNS deletion of the GLP-1R develop conditioned taste aversion (CTA) to lithium chloride but not to liraglutide (Sisley et al., 2014)