And the extra cushioning typically means less pain
When were slowing digestion, that can potentially [lead] to more bacteria where its not supposed to be: in the small intestine, Missimer explains
The pivotal Phase 2 trial a 48-week study published in The New England Journal of Medicine in 2023 produced these results in adults with obesity (and no diabetes), at the highest dose of 12 mg weekly: Average weight loss of around 24% from baseline A clear dose-response, with even the 4 mg dose producing roughly 17% weight loss Continued weight loss right up to the 48-week endpoint, with no plateau in sight For context, similar Phase 2 data for Wegovy showed around 15% weight loss at 68 weeks
Some people also report bloating, burping, or tiredness
In addition, this method has also been used in biomarker research for diseases such as diabetes and obesity
For instance, you might need a personalized dose or an allergen removed