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Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in noninsulin-dependent diabetes mellitus: A population-based study

[10] The first amylin analogue to reach the clinic, pramlintide, demonstrated that the pathway could be drugged, but native-style amylin analogues are short-acting and were used as multiple-daily injections, which limited their appeal for weight management

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The following antibody and stain panel was used for subsequent flow cytometry analysis: Sytox blue (Thermo Fisher Scientific, S34857, 1 M), CD31-BV605 (BioLegend, 303122), CD45-BV510 (BioLegend, 368526, lot B373428), CD44-AF647 (Novus Biologicals, NB500-481AF647), TFR1-PE (BioLegend, 334106) and FAP-AF750 (Novus Biologicals, FAB3715S-100UG)

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If not treated, they can cause lasting damage