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Unlike common skin cancers that arise from cells in the outermost layer of skin, dermatofibrosarcoma protuberans (DFSP) is an extremely rare cancer that arises from cells in the deepest layer of the skin, known as the dermis

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Loss of GSH homeostasis as occurs in ageing, chronic inflammation, and metabolic disease shifts S-glutathionylation patterns and dysregulates the signalling networks that depend on them

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