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Exercise has been shown to diminish the activity and expression of METTL14 in the thoracic aorta of atherosclerotic mice, thereby inhibiting METTL14-mediated m6A modification on NEAT1 mRNA, which suppresses the expression of NEAT1, and consequently inhibits pyroptosis in ECs to alleviate atherosclerosis (Yang et al., 2023)
5.2 Is It Safe for Everyone
Increased lipid peroxidation in sera of ALS patients: A potential biomarker of disease burden
In particular, exosomes derived from HEK293 cells treated with interferon- (INF-) carry a higher amount of OCTN2 with respect to exosomes derived from untreated cells
The heart and liver are specific targets of the complication