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This means retatrutide could realistically become available in the UK from 2028 at the earliest, though this timeline may change depending on trial outcomes and regulatory decisions
Ozempic, made by Novo Nordisk, is FDA-approved to manage blood sugar in patients with type 2 diabetes and to treat chronic kidney disease in diabetic patients
ARA-290 has demonstrated actual small nerve fiber regrowth in human clinical trials, measured by corneal confocal microscopy
however, they had elevated circulating levels of insulin, leptin, peptide YY (PYY), C-peptide 2, gastric inhibitory polypeptide (or glucose-dependent insulinotropic polypeptide [GIP]), amylin, and glucagon compared with WT controls (Figure 2, AH)
Insulin dosing can be tricky
We don't want that
