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This response involves multiple cell types

Although it has been known both in humans and rats that mucosal GSH becomes depleted in colitis (Buffinton et al, 1995

A small subset of participants, approximately 12%, continued losing through week 48 without plateauing

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Previous serious hypersensitivity reactions, current pregnancy (especially for weight-loss indications), active pancreatitis and severe gastroparesis generally contraindicate use