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Meta-analyses of randomized trials corroborate these findings: one large review of 27 RCTs reported no significant difference in suicidality between GLP-1 RAs and placebo (RR 0.76) [48], while another meta-analysis including 25 trials similarly showed no association across multiple subgroups and endpoints (RR 0.84) [49]

Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage

However, more studies are required to exactly define the best dose and duration of intervention

10.1002/advs.202103820 36 HassaniA.Avci

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