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Using the same spot repeatedly leads to lipohypertrophy, hardened fatty deposits that impair absorption

Glutathione helps convert toxins into water-soluble compounds, making it easier for the body to excrete them (Anderson et al., 2021)

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A study published in JHEP Reports in 2025 followed 29 participants with liver disease over 12 weeks

However, the ability of cells to synthesize glutathione declines in certain disease states as well as part of ageing, probably due to lower levels of glutathione reductase enzyme