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This mechanism is responsible for the production of antigen-specific IgE ( Figure 1 ) (180)
It can also reduce inflammation and oxidative stress at the cellular level
Garcia RCT, Torres LL, Dati LMM, Loureiro APM, Afeche SC, Sandoval MRL, Marcourakis T (2019) Anhydroecgonine Methyl ester (AEME), a cocaine pyrolysis product, impairs glutathione-related enzymes response and increases lipid peroxidation in the hippocampal cell culture
In addition, LipRSV treatment was associated with reduced BDNF and NGF levels, further indicating that redox modulation was not paralleled by neurotrophin restoration.Together, these results suggest limited therapeutic benefit of the formulation under the experimental conditions tested and highlight the complexity of linking redox modulation to functional behavioral outcomes in ASD models
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