[5] Its expansion into tendon, ligament, muscle, and bone research came later, largely from the same group of investigators
It is essential for DNA synthesis, red blood cell formation, and neurological function
Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity
See our B12 page for more detail
The arginate form is of particular interest in gastrointestinal research where oral administration routes are being studied
Yes, Voluma is more expensive for any doctor to buy from the manufacturer than Juvederm, and so thats why its more expensive for the patient, as well