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Individuals with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not use GLP-1 agonists
Con: IV has the worst side effects and can include allergic reactions in extreme cases
However, cases of concomitant deficiencies involving B 12 with either B 1 or B 6 remain rare, suggesting distinct risk factors and clinical presentations for each vitamin deficiency
We recommend discussing NAION risk with healthcare providers before starting GLP-1 therapy
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