The length of time vitamin B12 to become effective depends on different health-related aspects that could slow down the process
SC Injection Sites : Common sites include the abdomen (avoiding a 2-inch radius around the navel), outer area of the upper arm, or thigh
Mild redness can calm down
Because its a water-soluble vitamin, any excess that isnt used should be flushed from the body and not pose too much risk (not the case with fat-soluble vitamins like vitamin A)
Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement
Supplementing with vitamin B12 lowers homocysteine levels and may improve mood, particularly in response to stress