dpp 4 inhibitors and glp 1 agonists together Dipeptidyl Peptidase (DPP)-IV with Antioxidant Potential Isolated from Natural Sources: A Novel Approach for the Management of Diabetes The Role of DPP-4 Inhibitors

Chronic cortisol elevation accelerates myofibrillar protein breakdown through ubiquitin-proteasome pathway upregulation, reduces satellite cell proliferation, and impairs insulin-mediated glucose uptake in myocytes

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U., Rosien, U

Sica, J

Mitochondrial-mediated ROS cause oxidative damage to cellular structures, particularly mitochondrial DNA, somatic mutations, genome instability, inactivation of tumor suppressor genes, alterations in metabolic and signaling pathways with simultaneous activation of compensatory antioxidant mechanisms, all of which contribute to cell transformation and thus promote various types of cancer [42]

2018 Nov 6;18(22):3379-3392