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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin

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The approval of Exxuawhich Houstonbased Fabre-Kramer states is the first and only approved antidepressant for adults with MDD that works through the selective agonism of 5HT1a receptors to modulate serotonin throughout the central nervous systemwas hard won