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But as cancer care evolves, an important question emerges: can one endpoint always provide all the answers needed for every decision

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The new research published in April 2026 showed improved blood pressure and cholesterol markers in participants, but a dedicated cardiovascular outcomes trial with hard endpoints is still in progress

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According to available data in non-surgical patients, early treatment response (13 months) to the weight loss drug seems to be a good predictor of long-term weight maintenance [31,32,33,34]

As discussed above, a study of the enterogastrone effects of GLP-1 and PYY in dogs, where the GLP-1 receptor antagonist exendin 939 was incapable of blocking the inhibitory actions of GLP-1 (71), suggested that another receptor was involved