The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Unlicensed intravenous glutathione infusions, sometimes offered through private 'wellness' clinics, carry additional risks including infection, contamination, and anaphylaxis
Additional Glacial Acetic Acid and/or Sodium Acetate may have been used to adjust pH
Provider evaluation is required before treatment
Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapypotential markers for predicting breast cancer recurrence
Typical applications include glutathione S-transferase phase-II conjugation assays, glutathione peroxidase and glutathione reductase coupled assays, GSH/GSSG ratio determination as a redox readout in cultured cells, protein S-glutathionylation studies, and ferroptosis models where glutathione availability governs glutathione peroxidase 4 activity and therefore phospholipid hydroperoxide handling (Yang et al., Cell, 2014)