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Discussion Although many antidepressants with different mechanisms are being used, a number of patients have not achieved appropriate therapeutic effects

These effects are usually most noticeable when first starting or increasing doses, though they often improve as your body adjusts

6 In the EXAMINE trial, a safety signal for increased risk of hospitalisation for heart failure was identified with alogliptin, particularly in people with a history of heart failure

doi: 10.3389/fmicb.2019.01423 30 DalileB.van OudenhoveL.VervlietB.VerbekeK

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