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Description

People with stomach and intestinal conditions such as celiac disease and Crohns disease may struggle to absorb enough B12 from their food

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However, for anyone with absorption issues (like pernicious anemia or IBD), oral supplements are often insufficient

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When to Adjust Dosing Increase dose if: After 4-6 weeks at current dose, no measurable body composition changes occur, youre tolerating current dose without side effects, youre below the upper clinical range (1 mg daily), and your physician approves escalation based on comprehensive assessment

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The use of methotrexate may additionally invalidate diagnostic assays for folic acid and vitamin B12

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