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This is more than most existing weight loss drugs, including popular GLP-1 receptor agonists such as semaglutide and tirzepatide, which typically demonstrate a weight reduction of 15 to 20 percent at best

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Recognizing Plateaus and When to Reassess Your Dose A weight loss plateau at six monthsdefined as three weeks without scale movementdoes not mean semaglutide has stopped working

That reality matters, because it protects patients from disappointment and helps them choose a plan that is actually worth their time and money