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A study by Eder et al

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By day 35, it falls to approximately 60 percent, making the solution effectively unusable for research purposes

As mitochondria are major source of ROS, chronic impairment of any kind of mitochondrial function overproduces ROS and triggers a self-removal signal, or mitophagy, to eliminate the further oxidative environment (Schofield and Schafer 2021)

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