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In extreme cases, people with pernicious anemia or a related condition known as vitamin B12 deficiency myelopathy can develop nerve damage related to vitamin B12 deficiency

It works systemically, not locally: Unlike BPC-157, which targets a specific injury site, TB-500 travels through the entire body and finds damaged tissue wherever it is, making it effective for diffuse or multi-site injuries

Each ingredient on its own is either Category A (B) or essential with no evidence of harm at normal levels (B, B, B) or Category C in very high doses (niacin)

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The rotator cuff alone accounts for nearly 4.5 million physician visits each year in the United States

For health and safety, the product must be unopened