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Comparing These Four Peptides | Compound | Primary Target | Main Effect | |---|---|---| | Sermorelin | GHRH Receptor | Stimulates endogenous GH release | | CJC-1295 | GHRH Receptor | Sustained GH stimulation | | Ipamorelin | Ghrelin Receptor (GHS-R1a) | Triggers GH secretion | | IGF-1 LR3 | IGF-1 Receptor | Direct tissue-level IGF signaling | For a deeper dive into the specific compounds available, see our Peptide Therapy Education page, which catalogs 23 active peptide compounds with full mechanism-of-action references

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Patients with HNF1A-MODY and HNF4A-MODY are initially sensitive to SU treatment, but glucose-stimulated insulin secretion in response to SUs decreases over time (at a rate of 1%4% per year), and patients often become unresponsive to SU treatment after 325 years.8 ,9 Although some patients remain responsive to SUs for more than 30 years, insulin treatment is frequently used for patients who become unresponsive to SUs

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If you experience any suspected side effects from any medicine licensed or otherwise you can report these to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk

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