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Furthermore, whether restoring proper MOL heterogeneity is essential for functional tissue regeneration remains unknown, requiring further investigation into how transcriptional phenotypes translate to MOL structure and function

There are two findings in this study that are seemingly contradictory to existing literature

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Decline in level of reduced glutathione has often been considered to be indicative of increased oxidative stress23

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Total RNA isolation and real-time PCR Total RNA was isolated from cells and tissues using TRIzol reagent (Beyotime, China) and NanoDrop (Thermo Fisher Scientific, USA) was utilized for RNA concentration measurement