9amHealth, a Fierce Healthcare Fierce 15 honoree in 2024, was backed by Cigna to the tune of $9.5 million in early 2024.
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Analyses were based on the in-trial period, which was the time from randomization to the end-of-trial visit, death, withdrawal of consent or last contact with a trial site, whichever occurred first
Clinically, RBC transfusion efficacy is monitored using hemoglobin increments, a surrogate measure, and transfusions are guided by threshold hemoglobin values or the extent of surgical blood loss
However, the drug was subsequently overtaken by Pfizers Lipitor (FDA-approved in 1996), which generated ~$100B in sales from 1992 to 2017