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In animal studies, GLP1-agonists were associated with reduced fetal weight and/or growth, delayed ossification and skeletal variants, usually associated with a reduction in maternal weight gain and decreased food consumption
The specific risks identified in animal models include potential effects on pancreatic development and metabolic organ formation during critical windows of fetal growth
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The BBB expresses a large number of SLC transporters, among them the members of the ASCT and SNAT alanine carrier families [27]
Jiang NM, Cowan M, Moonah SN, Petri WA (2018) The Impact of Systemic Inflammation on Neurodevelopment
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