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The rhythmic muscle contractions that move stool through the colon decrease in frequency and amplitude

***Lpez Almaraz R, Lpez Gutirrez JC, Belendez Bieler C, Herrero Hernndez A, Mateos Gonzlez ME y Ramrez Villar G

Sublingual administration, which bypasses the gastrointestinal tract, appears to be equally effective as IM injections while being less invasive and more cost-efficientparticularly in patients with atrophic gastritis, post-gastrectomy status, or conditions that impair intrinsic factor-mediated absorption, where long-term intervention is often required

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This blog explains why they work well together, what science says about safety, and how to use them responsibly

European Journal of Pharmaceutics and Biopharmaceutics, 86 (2), 251259