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Last reviewed: June 6, 2026 Last updated: June 6, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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If youre experiencing any of the following issues, it could be a sign that youre suffering from neuropathy: Nerve pain Numbness in the hands, legs, arms, and feet Pain in the head and spine Balance and coordination issues Weakness in the muscles Burning sensations Sharp, sudden pain Neuropathy in the feet or legs can lead to sleep disruptions too

Haematological parameters typically normalise within approximately 8 weeks of appropriate treatment

Prescribers should also be aware that the American Academy of Pediatrics policy statement on off-label prescribing recommends that clinicians "use the best available evidence, inform families clearly about the off-label nature of the treatment, and document the clinical rationale thoroughly" [14]

Everyone needs vitamin B12, and most people get enough through their diet