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The rate of first-time T2D diagnoses within 15 days of a GLP-1 prescription was 2.1x higher for people with Class 3 obesity compared to those with overweight (BMI 27 30)

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The trial offered enrollees in a different study comparing Zepbound to Wegovy an opportunity to be re-randomized to take orforglipron or a placebo for another year

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ROS-induced impairment of the IFN response occurs in murine herpes virus infection, with the inhibition taking place downstream of cytoplasmic DNA sensing 59