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AD is characterized by two core pathologies, formation of amyloid- plaques and neurofibrillary tangles

Their unique ability to stimulate collagen production, provide antioxidant protection, and enhance skin barrier function simultaneously addresses multiple aspects of the aging process in a single ingredient

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Isatinimino-acridinedione core 46 Diaryl triazole analogs have been shown to induce dual COX-2/TNF- inhibitory activities in previous studies (122, 123)

Rather paradoxically, it has also been highlighted that GSHand notably its catabolites, as originated by metabolism by gamma-glutamyltransferasecan promote oxidative processes, by participating in metal ion-mediated reactions eventually leading to formation of reactive oxygen species and free radicals