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In fact, combining DSIP with complementary therapies may provide synergistic benefits through multiple sleep-supporting pathways

This restricts blood flow, raises blood pressure, and impairs organ function 71 72

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Medications that block NET, including SNRIs like duloxetine and venlafaxine, tricyclic antidepressants, and atomoxetine, can worsen hyperadrenergic POTS by further preventing norepinephrine clearance

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