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Funding This work was supported by the National Institutes of Health (NIH) grants R01AG067331 and R01AG069206
Blood samples for pharmacokinetic analysis were collected up to 15 min pre-dose (day 1), and at 4, 8, 12, 18, 24, 30, 36, 48, 54, 60, 72, 84, 96 and 120 h post-dose
Metzendorf C, Lind MI
Inagi et al., 2010)
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In brief, acetyl-CoA produced by glucose transfers electrons to the electron transport chain through a series of redox reactions, thereby generating ATP through oxidative phosphorylation as well as ROS, which induce ferroptosis
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