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A potential benefit of L-carnitine in these patients is based on the fact that it can (i) increase the oxidation of long-chain fatty acids which accumulation may contribute to insulin resistance in skeletal muscle, and (ii) enhance glucose utilization by reducing acyl-CoA concentration within the mitochondrial matrix (see Biological Activities) (42)
This process involves the repositioning or restructuring of nucleosomes, thereby changing the accessibility of DNA to transcription factors and regulatory proteins, which in turn affects the expression of NRF2 target genes
However, ITCs such as SFN produced by bacteria during incubation were unstable in the culture medium, so their final concentration was insignificant
The Diagnosis and Treatment of Peripheral Lymphedema: 2020 Consensus Document
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Comparative analysis of peptide therapies in musculoskeletal disorders
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