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According to the stratified analysis, the effect would occur irrespective of the schemes used or the populations tested

Last week, an American drugmaker stated it has not yet received approval from Indias drug regulator for selling its obesity drug Tirzepatide for weight loss

1 Introduction Erectile dysfunction (ED), defined as the inability to achieve and maintain an erection sufficient for sexual intercourse, is estimated to occur in 20% of men over the age of 40 and the incidence increases with age ( A recent retrospective cohort study suggested that GLP-1RAs might have induced positive vasculature effects, thereby improving erectile function in patients with T2D ( Mendelian randomization (MR) can generate more reliable evidence with less confounding and reverse causation by using genetic variants related to the exposure or drug target for causal inference and prediction of potential adverse outcomes for a specific drug target ( 2 Methods 2.1 Study design The drug target MR analysis was employed to investigate whether GLP-1RAs causally link to the risk of ED ( Figure 1 )

Wegovy and Ozempic are both FDA-approved brand-name semaglutide medications manufactured by Novo Nordisk, not compounded preparations

However, this is based on one case report and a study with small sample size

Together, they are investigated for complementary activity across multiple endocrine and systemic pathways in experimental settings