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some report distinct dysfunction in 5FU-resistant models, and some, like our organoid model presented in Extended Data Fig
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Hemoconcentration: Dehydration reduces plasma volume, leading to hemoconcentration with higher concentrations of red blood cells and clotting factors, accelerating clotting processes
SIRT3 protects mitochondrial function directly
Its rapidly broken down in the liver into amino acids and excreted through urine and bile
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