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But what is the difference between the two

Pierce the skin with the needle and inject the B12 into the cat

That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it

What to Expect With B12 B12 is one of the fastest-acting injections

PMCID: PMC11050313.

Folate deficiency caused by a lack of dietary folate is more common in people who have a generally unbalanced and unhealthy diet, people who regularly misuse alcohol, and people following a restrictive diet that does not involve eating good sources of folate