The answer to this will vary from patient to patients based on a variety of factors
Clinical trial data shows that musculoskeletal complaints occur in tirzepatide users, but not at rates significantly higher than placebo
The most commonly reported side effects are gastrointestinal: nausea, vomiting, diarrhea, and constipation
Sikiric, P., Rucman, R., Seiwerth, S., et al
All they mean is you have to take a few precautions first
Methods Protocol and search strategy A literature search was conducted via PubMed, Google Scholar, SCOPUS, MEDLINE and EMBASE, which aimed to cover all relevant literature available between inception to January 17, 2025