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Duration of use typically ranges from 4-8 weeks for acute conditions to 6-8 weeks or longer for chronic plantar fasciitis

Some users take higher doses up to 2000 mcg daily without reported issues

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doi: 10.1080/14656566.2023.2219392 104 NguyenTParkerRHawkinsEHolkovaBYazbeckVKolluriAet al

Our findings indicate that hydrophobic interactions contribute more substantially to the interaction between the FOXO4 FHD and p53 TAD than electrostatic I nteractions