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In contrast, cells that undergo ferroptosis seem to exhibit distinct morphological characteristics such as shrunken and damaged mitochondria

Signal Transduct Target Ther (2022) 7(1):252

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4 Conclusion and outlook This article reviews the molecular mechanisms of ferroptosis-induced osteoporosis, summarizes the signaling pathways through which ferroptosis affects bone metabolism, and focuses on the three-dimensional regulatory network of iron metabolism disorder, lipid peroxidation and bone homeostasis imbalance

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