Increase gradually to avoid gas and bloating, which are already common during semaglutide dose escalation
A dosing review is simply one part of that process
The most commonly reported side effects are typically mild and transient, occasionally including minor gastrointestinal upset, nausea, or heartburn, particularly if the supplements are taken on an empty stomach or in excessively high doses all at once
The primary known effectdelayed gastric emptyingalters the normal digestive rhythm, which may contribute to changes in bowel habits in some individuals
Data analysed by two-way repeated measures ANOVA to assess main effect effects of treatment ( b , c , f , g , j , k and m ) and two-way ANOVA, multiple comparison, Bonferroni post hoc test ( h )
In some cases, bloating and gas may indicate gastroparesis (paralysis of the stomach due to ineffective contractions)