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Severe caloric restriction can exacerbate cold sensitivity and may compromise nutritional status

We also looked at efficacy how successful these prescribed drugs are in reducing weight on a population-wide basis

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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 14 An Overview of Similarities and Differences in Metabolic Actions and Effects of Central Nervous System Between Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) and Sodium Glucose Co-Transporter-2 Inhibitors (SGLT-2is) Authors Wen S , Nguyen T, Gong M, Yuan X, Wang C, Jin J, Zhou L Received 24 March 2021 Accepted for publication 15 June 2021 Published 29 June 2021 Volume 2021:14 Pages 29552972 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Konstantinos Tziomalos Song Wen, 1, * Thiquynhnga Nguyen, 1, * Min Gong, 1 Xinlu Yuan, 1 Chaoxun Wang, 1 Jianlan Jin, 1 Ligang Zhou 1, 2 1 Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai, 201399, Peoples Republic of China

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GABAergic Activity Withanolides, particularly withaferin A and withanolide A, are positive allosteric modulators of GABA-A receptors [8]