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Researchers should define the main question before selecting a model: whether the study is testing cytoprotection, migration, proliferation-associated endpoints, angiogenesis, extracellular matrix remodeling, endothelial signaling, or tissue-level recovery

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Normally, ghrelin binds to them and sends a signal from the hypothalamus to the pituitary gland that stimulates the release of human growth hormone (hGH)