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AHK-Cu's copper-binding structure benefits from SubQ administration because subcutaneous tissue expresses copper transport proteins (CTR1, ATP7A) at higher density than skeletal muscle

Perino A, Demagny H, Velazquez-Villegas L, Schoonjans K

More recent preclinical work has examined GHK-Cu in rodent models of pulmonary fibrosis, silicosis and airway remodelling, with oxidative stress and inflammatory signalling as the reported endpoints

So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced

Avoid presenting symptom improvement as proof of tissue regeneration

Epub 2012 Mar 9