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Targher G, Tilg H, Byrne CD (2021) Non-alcoholic fatty liver disease: a multisystem disease requiring a multidisciplinary and holistic approach

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Engaging all three pathways simultaneously drives glucose-dependent insulin secretion through the two incretin arms while adding glucagon-receptor agonism implicated in energy expenditure, the pharmacological rationale that distinguishes it from single (GLP-1 (Sema)) and dual (GLP-2 (Triz)) incretin agonists

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