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A Multi-Center, Open-Label, Phase I Study of Single Agent RG7112: A First in Class p53-MDM2 Antagonist, in Patients with Relapsed/Refractory Acute Myeloid and Lymphoid Leukemias (AML/ALL) and Refractory Chronic Lymphocitic Leukemia/Small Cell Lymphocytic Lymphomas (CLL/SCLL)

Healing cascade activation may begin quickly, but measurable structural repair in intestinal lining models takes longer

Minimize room-temperature exposure

This includes applying evidence-based criteria such as BMI thresholds, diagnosis history, and documentation of prior lifestyle interventions

Protocol 3: long-term maintenance (for persistent mild symptoms) Goal: Comfortable long-term adherence with minimal GI disruption

Supports fat metabolism