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Factors like environmental pollution, poor diet, and chronic stress can also deplete our internal stores

doi: 10.7717/peerj.17416 49 LaiJGongLLiuYZhangXLiuWHanMet al

Another assumption is that a malfunction of the hypothalamicpituitaryadrenal (HPA) axis, which also contributes to the pathophysiology of depression, leads to upregulation of vitamin D receptor expression in these areas and increased vitamin D activity due to the presence of the enzyme 1-alpha-hydroxylase

Final isolation, characterization and activity test

Current research indicates that Epithalon is generally well-tolerated in studies

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